Corpus ID: 25723892

Inhibitory effect of oxatomide on oxygen-radical generation and peptide-leukotriene release from guinea pig eosinophils.

@article{Ohmori1998InhibitoryEO,
  title={Inhibitory effect of oxatomide on oxygen-radical generation and peptide-leukotriene release from guinea pig eosinophils.},
  author={K. Ohmori and H. Manabe and K. Akuta-Ohnuma},
  journal={Arzneimittel-Forschung},
  year={1998},
  volume={48 1},
  pages={
          43-6
        }
}
  • K. Ohmori, H. Manabe, K. Akuta-Ohnuma
  • Published 1998
  • Chemistry, Medicine
  • Arzneimittel-Forschung
  • Eosinophils are prominent inflammatory cells which play a critical role in the pathogenesis of allergic diseases and bronchial asthma. The aim of this experiment was to examine the effects of oxatomide (CAS 60607-34-3, KW-4354), an antiallergic agent, on oxygen-radical generation and peptide-leukotriene (p-LT) release from guinea pig eosinophils. Ketotifen (CAS 345080-13-7) and epinastine (CAS 80012-43-7) were used as reference drugs. Eosinophils were isolated from the peritoneal exudate of… CONTINUE READING
    Oxatomide inhibits Interleukin-8 release from respiratory epithelial cells