Inhibitory effect of hexane fraction from Myagropsis myagroides on pancreatic α-amylase in vitro.

@article{Pak2015InhibitoryEO,
  title={Inhibitory effect of hexane fraction from Myagropsis myagroides on pancreatic $\alpha$-amylase in vitro.},
  author={Won Min Pak and Koth-Bong-Woo-Ri Kim and Min-Ji Kim and Ji-young Cho and Dong Hyun Ahn},
  journal={Journal of microbiology and biotechnology},
  year={2015},
  volume={25 3},
  pages={
          328-33
        }
}
A Myagropsis myagroides (Mm) methanol extract showed α-amylase inhibitory activity of 13% at a concentration of 5 mg/ml. Results showed that the hexane fraction from the Mm methanol extract exhibited α-amylase inhibitory activity with an IC50 value of 4.24 mg/ml. The hexane fraction was separated using silica-gel column chromatography, and six subfractions were obtained. The fraction eluted with CHCl3:MeOH = 50:1 showed the highest α-amylase inhibitory activity with an IC50 value of 0.72 mg/ml… 
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