Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat.

@article{Jiang2007InhibitoryEO,
  title={Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat.},
  author={Qing-song Jiang and Xie-nan Huang and Zhi-kai Dai and Gui-zhong Yang and Qi-xin Zhou and Jing-Shan Shi and Qin Wu},
  journal={Journal of ethnopharmacology},
  year={2007},
  volume={111 3},
  pages={567-72}
}
Ginseng, the root of Panax ginseng, has been used as folk medicine in the treatment of various diseases for thousands of years in China. Ginsenoside Rb1 (Rb1), one of the effective components of ginseng, has been reported to release nitric oxide and decrease intracellular free Ca2+ in cardiac myocytes, both of which play important roles in antihypertrophic effect. This study was to investigate the potential effect of Rb1 on right ventricular hypertrophy (RVH) induced by monocrotaline (MCT) and… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
Heart AtriumDirect posterosuperior toHeart Ventricle
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
Heart AtriumDirect continuous withHeart Ventricle
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
Heart VentricleDirect continuous withHeart Atrium
After 2 weeks , significantly hypertrophic reactions , including RVH index and the expressions of atrial natriuretic peptide mRNA , appeared in right ventricle of all MCT - treated animals ( p < 0.05 ) , which were significantly decreased with some improvements of myocardial pathomorphology in both Rb1 prevention- and therapy - groups ( p < 0.05 ) .
All Topics