Inhibitory effect of chlordecone and mirex on steroid synthesis in Y-1 cells.

  • Walter P. Warner
  • Published 1987 in
    Journal of environmental pathology, toxicology…


Chlordecone is known to bring about alterations in the endocrine systems of a variety of animals. The present study was undertaken to investigate the possibility of a direct effect of the insecticide on steroid-secreting tissues. Technical grade chlordecone produced a dose-dependent inhibition of steroidogenesis in cultured mouse adrenal tumor cells (Y-1… (More)


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