Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line

@article{RajendraPrasad2010InhibitoryEO,
  title={Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line},
  author={N Rajendra Prasad and Arumugam Karthikeyan and Subburayan Karthikeyan and Bandugula Venkata Reddy},
  journal={Molecular and Cellular Biochemistry},
  year={2010},
  volume={349},
  pages={11-19}
}
Caffeic acid (3,4-dihydroxy cinnamic acid) (CA) is naturally found in fruits, vegetables, olive oil, and coffee. This study was undertaken to evaluate the anticancer effect of caffeic acid on HT-1080 human fibrosarcoma cell line. The antiproliferative effect of caffeic acid was determined by MTT assay, and the oxidative stress was determined by lipid peroxidation, changes in the enzymatic, and non-enzymatic antioxidant status. To understand the mode of antiproliferative effect of CA, the… 
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