Corpus ID: 33296629

Inhibitory effect of acetylcholine on glycogenolysis in the isolated guinea-pig heart.

@article{Vincent1963InhibitoryEO,
  title={Inhibitory effect of acetylcholine on glycogenolysis in the isolated guinea-pig heart.},
  author={N. H. Vincent and S. Ellis},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1963},
  volume={139},
  pages={
          60-8
        }
}
  • N. H. Vincent, S. Ellis
  • Published 1963
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental therapeutics
  • In perfused guinea-pig hearts acetylcholine antagonized completely the glycogenolytic effect of epinephrine. By electrically controlling the ventricular rate, the inhibitory effect of acetylcholine upon epinephrine-induced glycogenolysis was shown to be independent of the negative chronotropic action of acetylcholine. Acetylcholine alone did not elevate significantly cardiac glycogen. Dichloroisoproterenol inhibited the glycogenolytic, chronotropic, and inotropic effects of epinephrine… CONTINUE READING

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