Inhibitory effect of PGF-2 alpha on hCG-stimulated progesterone production in vitro by luteal cells from guinea-pigs at different stages of the oestrous cycle.

@article{Richardson1982InhibitoryEO,
  title={Inhibitory effect of PGF-2 alpha on hCG-stimulated progesterone production in vitro by luteal cells from guinea-pigs at different stages of the oestrous cycle.},
  author={Malcolm C. Richardson and Margaret J Peddie},
  journal={Journal of reproduction and fertility},
  year={1982},
  volume={66 1},
  pages={117-22}
}
Suspensions of luteal cells were prepared by collagenase dispersion of guinea-pig corpora lutea obtained at specific times during the oestrous cycle. Luteal cells incubated with hCG produced increased amounts of progesterone. For Days 3--13 of the oestrous cycle, the concentrations of hCG required for 50% of the maximum response were within the range, 1 x… CONTINUE READING