Inhibitory effect of Epigallocatechin gallate on ovarian cancer cell proliferation associated with aquaporin 5 expression

@article{Yan2011InhibitoryEO,
  title={Inhibitory effect of Epigallocatechin gallate on ovarian cancer cell proliferation associated with aquaporin 5 expression},
  author={Chunxiao Yan and Jianhua Yang and L. R. Shen and Xuejun Chen},
  journal={Archives of Gynecology and Obstetrics},
  year={2011},
  volume={285},
  pages={459-467}
}
Abnormal expression of aquaporin 5 (AQP5) is associated with ovarian cancer infiltration, metastasis and angiogenesis. AQP 5 expression and apoptosis have been shown to be closely related to nuclear transcription factor NF-κB. In this study, we investigated the inhibition of cell proliferation and the induction of apoptosis by Epigallocatechin gallate (EGCG), a potential anti-cancer drug, in the ovarian cancer cell line SKOV3 as well as the effect of EGCG on AQP5 expression and its possible… CONTINUE READING

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