Inhibitory control of nociceptive responses of trigeminal spinal nucleus cells by somatosensory corticofugal projection in rat.

@article{Malmierca2012InhibitoryCO,
  title={Inhibitory control of nociceptive responses of trigeminal spinal nucleus cells by somatosensory corticofugal projection in rat.},
  author={Eduardo Malmierca and Yasmina B. Martin and Angel N{\'u}{\~n}ez},
  journal={Neuroscience},
  year={2012},
  volume={221},
  pages={115-24}
}
The caudal division of the trigeminal spinal nucleus (Sp5C) is an important brainstem relay station of orofacial pain transmission. The aim of the present study was to examine the effect of cortical electrical stimulation on nociceptive responses in Sp5C neurons. Extracellular recordings were performed in the Sp5C nucleus by tungsten microelectrodes in urethane-anesthetized Sprague-Dawley rats. Nociceptive stimulation was produced by application of capsaicin cream on the whisker pad or by… CONTINUE READING

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