• Biology, Medicine
  • Published in
    Canadian journal of…
    1997
  • DOI:10.1139/y97-033

Inhibitory control of GABAergic interneurons in the hippocampus.

@article{Freund1997InhibitoryCO,
  title={Inhibitory control of GABAergic interneurons in the hippocampus.},
  author={Tam{\'a}s F. Freund and Attila I. Guly{\'a}s},
  journal={Canadian journal of physiology and pharmacology},
  year={1997},
  volume={75 5},
  pages={
          479-87
        }
}
Hippocampal GABAergic interneurons are responsible for controlling the output and efficacy of synaptic input of large principal cell populations and, thereby, determine the oscillatory discharge patterns and synaptic plasticity in the hippocampus. Single interneurons are able to prevent repetitive firing of postsynaptic pyramidal cells (R. Miles, K. Tóth, A.I. Gulyás, N. Hájos, and T.F. Freund. Neuron, 16: 815-823, 1996), whereas on occasion a single pyramidal cell may be able to activate an… CONTINUE READING

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