Inhibitory breakdown and dementia of the Alzheimer type: a general phenomenon?

  title={Inhibitory breakdown and dementia of the Alzheimer type: a general phenomenon?},
  author={H{\'e}l{\`e}ne Amieva and Sylviane Lafont and S. Auriacombe and Nicolas Le Carret and Jean-François Dartigues and J. M. Orgogozo and Fabrigoule Colette},
  journal={Journal of clinical and experimental neuropsychology},
  volume={24 4},
Several recent studies have provided substantial support for the proposal that a decrease in inhibitory processing may play an important role in cognitive changes occurring in the early stages of Dementia of the Alzheimer Type (DAT). The question addressed by the present study was whether these deficits are the result of the failure of a general inhibitory mechanism, or whether DAT is associated with selective decreases in a subset of inhibitory processes. For this, a computerized battery of… CONTINUE READING

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