Corpus ID: 25003606

Inhibitory and lethal concentrations of 9-beta-D-arabinofuranosyladenine and its hypoxanthine-derivative versus herpes simplex virus, type 1.

@article{Williams1977InhibitoryAL,
  title={Inhibitory and lethal concentrations of 9-beta-D-arabinofuranosyladenine and its hypoxanthine-derivative versus herpes simplex virus, type 1.},
  author={B. Williams and E. Bailey and A. Lerner},
  journal={The Journal of laboratory and clinical medicine},
  year={1977},
  volume={89 4},
  pages={
          687-91
        }
}
Minimum inhibitory concentrations of 9-beta-D-arabinofuranosyladenine (ara-A, adenine arabinoside, vidarabine) and a purified preparation of 9-beta-D-arabinofuranosylhypoxanthine (arabinoslhypoxanthine, ara-Hx) at end points of 50% MIC50) and 100% (MIC100) reduction to challenges of approximately 50 p.f.u. of herpes simplex virus, type 1 (HSV-1) were determined in vero renal tissue cultures. Adenosine deaminase is universally present in tissue cultures and serum. These same tests were repeated… Expand
1 Citations
Antiviral Drugs and Interferon: The Molecular Basis of Their Activity
  • Y. Becker
  • Biology
  • Developments in Molecular Virology
  • 1984
  • 54
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