Inhibitory and bactericidal effect of Artilysin® Art-175 against colistin-resistant mcr-1-positive Escherichia coli isolates.

  title={Inhibitory and bactericidal effect of Artilysin{\textregistered} Art-175 against colistin-resistant mcr-1-positive Escherichia coli isolates.},
  author={Eva Schirmeier and P. Zimmermann and Veronika Hofmann and M. Biebl and H. Gerstmans and Veerle E. T. Maervoet and Y. Briers},
  journal={International journal of antimicrobial agents},
  volume={51 3},
The number of mcr-1-positive isolates has increased tremendously since the first report of the plasmid-mediated colistin– resistance mechanism [1]. Isolates with the transferable gene have been identified in (food) animals, various types of meat, vegetables and humans in more than 30 countries [2]. Consequently, the Chinese government has forbidden the use of colistin as a growth promotor for the veterinary sector. The European Medicines Agency now suggests to classify colistin in a higher-risk… Expand
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