Inhibitory activity of a phytochemically characterized fraction from Streptocaulon juventas on lung cancer in nude mice.

@article{Han2010InhibitoryAO,
  title={Inhibitory activity of a phytochemically characterized fraction from Streptocaulon juventas on lung cancer in nude mice.},
  author={Na Han and Jingyu Yang and Linwei Li and Bin Xiao and Sha Sha and Lequan Tran and Jun Yin and Chunfu Wu},
  journal={Planta medica},
  year={2010},
  volume={76 6},
  pages={
          561-5
        }
}
In the present study, a 75% ethanol extract of Streptocaulon juventas (SJ), which had a strong inhibitory effect on the proliferation of human lung A549 adenocarcinoma cells, was subjected to bioassay-guided fractionation. The most active fraction (SJF) was obtained using a macroreticular resin column followed by a silica-gel column. Then its in vivo effect on lung cancer was investigated in athymic nude mice with A549 tumors while its effects on body weight, blood biochemical indicators, and… 

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