Inhibitory action of erythromycin on bacteriophage SPO1 multiplication in sporulating cells of Bacillus subtilis 168

@article{Hirochika1980InhibitoryAO,
  title={Inhibitory action of erythromycin on bacteriophage SPO1 multiplication in sporulating cells of Bacillus subtilis 168},
  author={Hirohiko Hirochika},
  journal={Molecular and General Genetics MGG},
  year={1980},
  volume={179},
  pages={581-588}
}
Erythromycin (2–4 μg/ml) was found to inhibit specifically multiplication of SPO1 in sporulating cells of an erythromycin-resistant, conditional asporogenous mutant of Bacillus subtilis 168 thy - trp -, Ery1040. In contrast, streptomycin (150–200 μg/ml) which inhibits protein synthesis to a similar extent as erythromycin did not inhibit SPO1 multiplication severely, suggesting that the inhibition of SPO1 multiplication by erythromycin is not caused by an overall inhibition of protein synthesis… CONTINUE READING