Inhibitory Influence of Agmatine in Ethanol Withdrawal-Induced Depression in Rats: Behavioral and Neurochemical Evidences.

@article{Chimthanawala2019InhibitoryIO,
  title={Inhibitory Influence of Agmatine in Ethanol Withdrawal-Induced Depression in Rats: Behavioral and Neurochemical Evidences.},
  author={Niyamat Chimthanawala and Shruti Patil and Rishabh Agrawal and Nandkishor R Kotagale and Milind Janraoji Umekar and Brijesh Gulabrao Taksande},
  journal={Alcohol},
  year={2019}
}
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5 Citations

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References

SHOWING 1-10 OF 61 REFERENCES
Effects of agmatine on ethanol withdrawal syndrome in rats
Agmatine blocks ethanol-induced locomotor hyperactivity in male mice.
Lobeline attenuates ethanol abstinence-induced depression-like behavior in mice.
Agmatine, an endogenous imidazoline receptor ligand modulates ethanol anxiolysis and withdrawal anxiety in rats.
Agmatine Inhibits Behavioral Sensitization to Ethanol Through Imidazoline Receptors
TLDR
Inhibition of EtOH sensitization by Agmatine is mediated through imidazoline receptors and project agmatine and imidrazoline agents in the pharmacotherapy of alcohol addiction.
Single administration of agmatine reverses the depressive-like behavior induced by corticosterone in mice: Comparison with ketamine and fluoxetine
Agmatine produces antidepressant-like effects in two models of depression in mice
TLDR
Data demonstrate that agmatine elicited a significant antidepressant-like effect through a mechanism that seems to involve an interaction with NMDA receptors, the L-arginine-nitric oxide pathway and &agr;2-adrenoceptors.
Acute agmatine administration, similar to ketamine, reverses depressive-like behavior induced by chronic unpredictable stress in mice
Antidepressant and pro-neurogenic effects of agmatine in a mouse model of stress induced by chronic exposure to corticosterone
Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice.
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