Inhibitory Effects of Carrageenans on Endotoxin-Induced Inflammation

  title={Inhibitory Effects of Carrageenans on Endotoxin-Induced Inflammation},
  author={Irina M. Yermak and Aleksandra V. Volod’ko and Eleonora Izrailevna Khasina and Viktoriya N. Davydova and Evgeniy Anatolievich Chusovitin and Dmitry L. Goroshko and Anna O. Kravchenko and Tamara F. Solov’eva and Victor V. Maleev},
  journal={Marine Drugs},
The inhibitory effects of carrageenans (CRGs) on lipopolysaccharide (LPS) induced inflammation in a mouse model of endotoxemia and in complex therapy of patients with enteric infections of Salmonella etiology were studied. The atomic force microscopy (AFM) examination of LPS and its mixture with CRGs showed that the LPS morphology is significantly changed under the action of κ- and κ/β-CRGs. CRGs were able to increase the synthesis of anti-inflammatory interleukin 10 (IL-10) in vitro, and, at… 

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