Inhibitory Effect of Serotonin Antagonist on Leukocyte-Endothelial Interactions In Vivo and In Vitro

Abstract

BACKGROUND Although 5-HT2A serotonergic antagonists have been used to treat vascular disease in patients with diabetes mellitus or obesity, their effects on leukocyte-endothelial interactions have not been fully investigated. In this study, we assessed the effects of sarpogrelate hydrochloride (SRPO), a 5-HT2A receptor inverse agonist, on leukocyte… (More)
DOI: 10.1371/journal.pone.0147929

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@inproceedings{Kataoka2016InhibitoryEO, title={Inhibitory Effect of Serotonin Antagonist on Leukocyte-Endothelial Interactions In Vivo and In Vitro}, author={Hiroshi Kataoka and Yuno Ariyama and Michiyo Deushi and Mizuko Osaka and Kosaku Nitta and Masayuki Yoshida and Gianfranco Pintus}, booktitle={PloS one}, year={2016} }