Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats.

@article{Islam2017InhibitorsOS,
  title={Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats.},
  author={Oliul Islam and Prashanth Patil and Sumanta K Goswami and Rema Razdan and Mohammed Naseeruddin Inamdar and Mohammed Rizwan and Jubin Mathew and Bora Inceoğlu and Kin Sing Stephen Lee and Sung Hee Hwang and Bruce D Hammock},
  journal={Cardiovascular therapeutics},
  year={2017},
  volume={35 3}
}
AIM We designed a study to evaluate the cardioprotective effect of two soluble epoxide hydrolase (sEH) inhibitors, 1-(1-propanoylpiperidin-4-yl)-3-(4-trifluoromethoxy)phenyl)urea (TPPU) and trans-4-{4-[3-(4-trifluoromethoxyphenyl)-ureido]cyclohexyloxy}benzoic acid (t-TUCB), in ischemia-reperfusion (IR) model. METHODS Cardioprotective effects of the sEH… CONTINUE READING