Inhibitors of retrovirus infection are secreted by several hamster cell lines and are also present in hamster sera.

@article{Miller1993InhibitorsOR,
  title={Inhibitors of retrovirus infection are secreted by several hamster cell lines and are also present in hamster sera.},
  author={Daniel G. Miller and A Dusty Miller},
  journal={Journal of virology},
  year={1993},
  volume={67 9},
  pages={5346-52}
}
We have previously shown that Chinese hamster ovary (CHO) cells are resistant to infection by gibbon ape leukemia virus and amphotropic pseudotype retroviral vectors because of the secretion of factors that inhibit retrovirus infection. Such factors were not secreted by any mouse or human cell lines tested. Secretion of the inhibitors and resistance to infection are abrogated by treatment of CHO cells with the glycosylation inhibitor tunicamycin. Here we show that the inhibitory activities… CONTINUE READING

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