Inhibitors of protein synthesis on 80S ribosomes phase shift the Gonyaulax clock.

Abstract

One-hour pulses of anisomycin (0.3 microM), streptimidone (30 microM) and cycloheximide (5 microM) caused strong phase-shifts (either advances or delays, of up to 12 h) in the circadian rhythm of the bioluminescence glow in the marine photosynthetic dinoflagellate, Gonyaulax polyedra. Similar pulses of emetine (0.1-100 microM) caused small (less than 4 h… (More)

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@article{Taylor1982InhibitorsOP, title={Inhibitors of protein synthesis on 80S ribosomes phase shift the Gonyaulax clock.}, author={W. R. Taylor and J. C. Dunlap and J. Woodland Hastings}, journal={The Journal of experimental biology}, year={1982}, volume={97}, pages={121-36} }