Inhibitors of nitric oxide synthase influence oocyte maturation in rats.

@article{JablonkaShariff1999InhibitorsON,
  title={Inhibitors of nitric oxide synthase influence oocyte maturation in rats.},
  author={Albina Jablonka-Shariff and Rita Basuray and Lisa M. Olson},
  journal={Journal of the Society for Gynecologic Investigation},
  year={1999},
  volume={6 2},
  pages={95-101}
}
OBJECTIVE To examine the effect of inhibiting nitric oxide synthase (NOS) on the number of ovulated oocytes and on oocyte meiotic maturation. METHODS Female Sprague-Dawley rats (25 days old) were superovulated with a subcutaneous injection of 10 U pregnant mare's serum gonadotropin, followed 52 hours later by a subcutaneous injection of 10 U human chorionic gonadotropin (hCG). Three hours before and 3 hours after hCG injection, the rats were treated orally with the vehicle (0.5… CONTINUE READING
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