Inhibitors of mammalian central nervous system selective amino acid transporters.

@article{Armer2000InhibitorsOM,
  title={Inhibitors of mammalian central nervous system selective amino acid transporters.},
  author={Richard E Armer},
  journal={Current medicinal chemistry},
  year={2000},
  volume={7 2},
  pages={
          199-209
        }
}
Central nervous system (CNS) selective amino acid transporters provide an important function in maintaining tonic extracellular levels of amino acids that act as neurotransmitters, synaptic modulators or neurotransmitter precursors. Small molecule inhibitors of these transporters have been postulated and in some cases demonstrated to be useful in the treatment of a range of CNS driven disorders such as epilepsy, anxiety, psychosis, depression, pain and neurodegenerative disease. Although much… CONTINUE READING