Inhibitors of cyclin dependent kinases: useful targets for cancer treatment.

Abstract

Cancer drug discovery is one of the most rapidly changing areas of pharmaceutical research. Uncontrolled proliferation is a hallmark of cancer cells. Over the past two decades, it has become increasingly clear that in many human cancers, hyperactivity of Cyclin Dependent Kinases (CDKs) is one of the mechanisms underlying the physiological hyper… (More)

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@article{Sharma2008InhibitorsOC, title={Inhibitors of cyclin dependent kinases: useful targets for cancer treatment.}, author={Pooja Sapra Sharma and R. Sharma and Rahul Tyagi}, journal={Current cancer drug targets}, year={2008}, volume={8 1}, pages={53-75} }