Inhibitors of apoptosis proteins (IAPs) expression and their prognostic significance in hepatocellular carcinoma


Similarly to other tumor types, an imbalance between unrestrained cell proliferation and impaired apoptosis appears to be a major unfavorable feature of hepatocellular carcinoma (HCC). The members of IAP family are key regulators of apoptosis, cytokinesis and signal transduction. IAP survival action is antagonized by specific binding of Smac/DIABLO and XAF1… (More)
DOI: 10.1186/1471-2407-9-125


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