Inhibitors of GlyT1 and GlyT2 differentially modulate inhibitory transmission

@article{Xu2005InhibitorsOG,
  title={Inhibitors of GlyT1 and GlyT2 differentially modulate inhibitory transmission},
  author={Tai-Xiang Xu and Neng Gong and Tian-Le Xu},
  journal={NeuroReport},
  year={2005},
  volume={16},
  pages={1227-1231}
}
The chronic effects of glycine transporter 1 and 2 inhibitors (sarcosine and ALX-1393, respectively) on miniature inhibitory postsynaptic currents were studied in cultured spinal neurons. We found that sarcosine increased the frequency of overall miniature inhibitory postsynaptic currents without affecting the ratio of glycinergic, mixed and GABAergic miniature inhibitory postsynaptic currents, whereas ALX-1393 changed the ratio by increasing the proportions of GABAergic and mixed miniature… 

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