Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance.

@article{PonzSarvis2011InhibitorOD,
  title={Inhibitor of differentiation-1 as a novel prognostic factor in NSCLC patients with adenocarcinoma histology and its potential contribution to therapy resistance.},
  author={Mariano Ponz-Sarvis{\'e} and Paul A Nguewa and Mar{\'i}a J Pajares and Jackeline Agorreta and Mar{\'i}a Dolores Ru{\'i}z Lozano and Miriam Redrado and Rub{\'e}n P{\'i}o and Carmen Behrens and Ignacio I. Wistuba and Carlos Enrique Garc{\'i}a-Franco and Jes{\'u}s Miguel Garc{\'i}a-Foncillas and Luis M. Montuenga and Alfonso Calvo and Ignacio Gil-Bazo},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2011},
  volume={17 12},
  pages={4155-66}
}
PURPOSE High inhibitor of differentiation-1 (Id1) levels have been found in some tumor types. We aimed to study Id1 levels and their prognostic impact in a large series of stages I to IV non-small cell lung cancer (NSCLC) patients. Experiments in cell lines and cells derived from malignant pleural effusions (MPE) were also carried out. EXPERIMENTAL DESIGN A total of 346 NSCLC samples (three different cohorts), including 65 matched nonmalignant tissues, were evaluated for Id1 expression by… CONTINUE READING

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