Inhibitor of 2' ,5′-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon: 83

Abstract

2',5'-oligoadenylate(2-5A) synthetase is an interferon(IFN)-induced enzyme, which has been considered to play a central role in antiviral activity. In general, the increased susceptibility to viral infections are common in severe combined immunodeficiency. Therefore, using human T lymphoblastoid cell line treated with deoxycoformycin as an in vitro model of… (More)
DOI: 10.1203/00006450-198507000-00103

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