Inhibitor development: patient-determined risk factors.

@article{Astermark2010InhibitorDP,
  title={Inhibitor development: patient-determined risk factors.},
  author={Jan Astermark},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2010},
  volume={16 102},
  pages={66-70}
}
The reasons that inhibitory factor VIII antibodies develop in only a fraction of patients with haemophilia A remain unclear, but studies of genetically related subjects have indicated that the immunological outcome of replacement therapy is to a large extent determined by patient-related risk factors. Non-genetic factors will also influence the inhibitor risk, since events challenging the immune system will elicit and stimulate immune regulatory processes with the potential of modifying the… CONTINUE READING

From This Paper

Topics from this paper.
25 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Similar Papers

Loading similar papers…