Inhibiton of IL 2 production after human allogeneic bone marrow transplantation.

@article{Azogui1983InhibitonOI,
  title={Inhibiton of IL 2 production after human allogeneic bone marrow transplantation.},
  author={Orly Azogui and Eliane Gluckman and Didier Fradelizi},
  journal={Journal of immunology},
  year={1983},
  volume={131 3},
  pages={
          1205-8
        }
}
Bone marrow transplantation (BMT) is currently used to treat patients with severe aplastic anemia or leukemia. Despite the use of an HLA identical sibling donor, however, the survival after BMT is reduced by the occurrence of two major immunologic complications: graft-vs-host disease and a long-lasting immune deficiency responsible for late infections. This immune deficiency could be explained by an imbalance of lymphocyte subpopulations reconstituted after transplant. The aim of the present… CONTINUE READING

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