Inhibition with N-acetylcysteine of enhanced production of tumor necrosis factor in streptozotocin-induced diabetic rats.

@article{Sagara1994InhibitionWN,
  title={Inhibition with N-acetylcysteine of enhanced production of tumor necrosis factor in streptozotocin-induced diabetic rats.},
  author={Mina Sagara and Jo Satoh and Xi – Ping Zhu and Kazuhiko Takahashi and Masahiro Fukuzawa and Gen Muto and Yasutoshi Muto and Takayoshi Toyota},
  journal={Clinical immunology and immunopathology},
  year={1994},
  volume={71 3},
  pages={333-7}
}
We previously reported that the in vivo production of the tumor necrosis factor alpha (TNF) was significantly enhanced after the onset of diabetes in spontaneous type 1 and 2 diabetic animals. In this report we confirmed the enhanced production of TNF in streptozotocin (STZ)-induced diabetes and then attempted to suppress the enhanced TNF production with N… CONTINUE READING