Inhibition-related activity in subgenual cingulate is associated with symptom severity in major depression

@article{Matthews2009InhibitionrelatedAI,
  title={Inhibition-related activity in subgenual cingulate is associated with symptom severity in major depression},
  author={Scott C. Matthews and Alan N. Simmons and Irina A Strigo and Peter J. Gianaros and Martin P. Paulus},
  journal={Psychiatry Research: Neuroimaging},
  year={2009},
  volume={172},
  pages={1-6}
}
Individuals with major depressive disorder (MDD) show impaired inhibitory control over negative thoughts. However, the brain mechanism underlying impaired inhibitory control in MDD has been incompletely described. The objective of this study was to examine brain function during inhibitory and error processing in a unique population of young, healthy, unmedicated MDD individuals. We hypothesized that MDD subjects would show clinically relevant alterations in brain activation in medial prefrontal… CONTINUE READING

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