Inhibition ofd-alanyl-d-alanine ligase in different bacterial species by amino phosphonic acids

@article{Lacoste2007InhibitionOL,
  title={Inhibition ofd-alanyl-d-alanine ligase in different bacterial species by amino phosphonic acids},
  author={Anne-Marie Lacoste and Mette N\ohr Poulsen and Andr{\'e} Cassaigne and Eug{\`e}ne Neuzil},
  journal={Current Microbiology},
  year={2007},
  volume={2},
  pages={113-117}
}
A comparative study was performed on the kinetic properties and the specificity ofd-alanyl-d-alanine ligases fromPseudomonas aeruginosa, Streptococcus faecalis, andStaphylococcus aureus, using some aminophosphonic acids and related compounds.dl-I-Aminoethylphosphonic acid was shown to be a competitive inhibitor of theP. aeruginosa andS. faecalis ligases… CONTINUE READING