Inhibition of voltage-gated calcium channels as common mode of action for (mixtures of) distinct classes of insecticides.

Abstract

Humans are exposed to distinct structural classes of insecticides with different neurotoxic modes of action. Because calcium homeostasis is essential for proper neuronal function and development, we investigated the effects of insecticides from different classes (pyrethroid: (α-)cypermethrin; organophosphate: chlorpyrifos; organochlorine: endosulfan… (More)
DOI: 10.1093/toxsci/kfu110

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