Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.

@article{Kendall1993InhibitionOV,
  title={Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.},
  author={Richard L. Kendall and Kenneth A. Thomas},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 22},
  pages={10705-9}
}
Vascular endothelial cell growth factor, a mitogen selective for vascular endothelial cells in vitro that promotes angiogenesis in vivo, functions through distinct membrane-spanning tyrosine kinase receptors. The cDNA encoding a soluble truncated form of one such receptor, fms-like tyrosine kinase receptor, has been cloned from a human vascular endothelial cell library. The mRNA coding region distinctive to this cDNA has been confirmed to be present in vascular endothelial cells. Soluble fms… CONTINUE READING
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