Inhibition of v-fms-induced tumor growth in nude mice by castanospermine.

@article{Ostrander1988InhibitionOV,
  title={Inhibition of v-fms-induced tumor growth in nude mice by castanospermine.},
  author={George K. Ostrander and N K Scribner and Larry R. Rohrschneider},
  journal={Cancer research},
  year={1988},
  volume={48 5},
  pages={1091-4}
}
Castanospermine, an indolizidine alkaloid isolated from the seeds of the chestnut tree Castanospermum australe, has been shown to prevent the normal glycosylational processing of the v-fms-transforming glycoprotein. v-fms-transformed cells grown in vitro in the presence of castanospermine accumulate immature forms of the glycoprotein that do not reach the… CONTINUE READING