Inhibition of tumor necrosis factor by curcumin, a phytochemical.

  title={Inhibition of tumor necrosis factor by curcumin, a phytochemical.},
  author={Marion M Chan},
  journal={Biochemical pharmacology},
  volume={49 11},
Curcumin, contained in the rhizome of the plant Curcuma longa Linn, is a naturally occurring phytochemical that has been used widely in India and Indonesia for the treatment of inflammation. The pleiotropic cytokine tumor necrosis factor-alpha (TNF) induces the production of interleukin-1 beta (IL-1), and, together, they play significant roles in many acute and chronic inflammatory diseases. They have been implicated in the pathogenesis of intracellular parasitic infections, atherosclerosis… CONTINUE READING