Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus.

@article{Falco2005InhibitionOT,
  title={Inhibition of thromboxane biosynthesis by triflusal in type 2 diabetes mellitus.},
  author={A Falco and Filippo Salvati and Ester Vitacolonna and Giuseppe Avellone and Antonio Pinto and Concetta Di Febbo and Enzo Ballone and Marta Di Nicola and Giovanni Ciabattoni and Giovanni Davı̀},
  journal={Atherosclerosis},
  year={2005},
  volume={183 2},
  pages={
          329-35
        }
}
Triflusal is an antiplatelet drug related to aspirin, with different pharmacological properties and a lower haemorrhagic risk. We aimed at comparing their effects on platelet and endothelial activation in type 2 diabetes mellitus (T2DM). In a randomized, double-blind, parallel group study, we compared the effects of three daily regimens (300, 600, and 900 mg) of triflusal, and aspirin (100mg/day) on urinary 11-dehydro-thromboxane (TX)B(2), index of in vivo platelet activation, ex vivo platelet… Expand
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