Inhibition of the tissue factor pathway of coagulation by recombinant nematode anticoagulant protein c2 during elective coronary stent implantation.

@article{Moons2004InhibitionOT,
  title={Inhibition of the tissue factor pathway of coagulation by recombinant nematode anticoagulant protein c2 during elective coronary stent implantation.},
  author={Arno H. M. Moons and Nick R. Bijsterveld and Karel T. Koch and Joost C M Meijers and Jan G. P. Tijssen and Tom van der Poll and Harry Roger B{\"u}ller and R. J. G. Peters},
  journal={Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation},
  year={2004},
  volume={12 2},
  pages={48-54}
}
BACKGROUND Exposure of tissue factor (TF) to the circulation during coronary stent implantation initiates coagulation activation and may contribute to the risk of thrombotic complications. In this study, we investigated whether inhibition of TF-factor VIIa by recombinant Nematode Anti-coagulant Protein c2 (rNAPc2) is able to suppress haemostatic and… CONTINUE READING