Inhibition of the mixed leukocyte reaction by alloantisera in man. II. Incidence and characteristics of MLC-inhibiting antisera from multiparous women.


The incidence of MLC-inhibiting antibodies was determined in 42 pregnancy sera. MLC's were carried out between the cells from the serum donor and her husband in the presence of nonimmune AB serum and the test serum. Fifty per cent of the sera reduced the MLC response to less than 40% of the control values. Only four sera had lymphocytotoxic activity. The… (More)