Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31.

@article{LeeHuang1995InhibitionOT,
  title={Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31.},
  author={Sylvia Lee-Huang and Philip Lin Huang and Aldar S. Bourinbaiar and Hao Chen and Hank F Kung},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 19},
  pages={
          8818-22
        }
}
MAP30 (Momordica anti-HIV protein of 30 kDa) and GAP31 (Gelonium anti-HIV protein of 31 kDa) are anti-HIV plant proteins that we have identified, purified, and cloned from the medicinal plants Momordica charantia and Gelonium multiflorum. These antiviral agents are capable of inhibiting infection of HIV type 1 (HIV-1) in T lymphocytes and monocytes as well as replication of the virus in already-infected cells. They are not toxic to normal uninfected cells because they are unable to enter… CONTINUE READING

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