Inhibition of the in vitro pituitary response to luteinizing hormone-releasing hormone by melatonin, serotonin, and 5-methoxytryptamine.

@article{Martin1977InhibitionOT,
  title={Inhibition of the in vitro pituitary response to luteinizing hormone-releasing hormone by melatonin, serotonin, and 5-methoxytryptamine.},
  author={Jo E. Martin and Joanne N. Engel and David C. Klein},
  journal={Endocrinology},
  year={1977},
  volume={100 3},
  pages={675-80}
}
The effects of pineal indole compounds on the response of the neonatal rat anterior pituitary gland to LH-releasing hormone (LHRH) were studied in organ culture. After 24 h of culture under control conditions, pituitary glands from 5-day-old female rats were routinely incubated for an additional 24 h with the test compounds. Medium LH content was determined… CONTINUE READING