Inhibition of the growth of transformed and neoplastic cells by the dipeptide carnosine.

Abstract

Human diploid fibroblasts growth normally in medium containing physiological concentrations of the naturally occurring dipeptide carnosine (beta-alanyl-L-histidine). These concentrations are cytotoxic to transformed and neoplastic cells lines in modified Eagle medium (MEM), whereas these cells grow vigorously in Dulbecco's modified Eagle medium (DMEM… (More)
DOI: 10.1038/bjc.1996.189

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