Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor.

@article{Cheng2002InhibitionOT,
  title={Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor.},
  author={Shinta Cheng and Sabrina R Brzostek and Suzanne R Lee and Anthony N. Hollenberg and Steven P. Balk},
  journal={Molecular endocrinology},
  year={2002},
  volume={16 7},
  pages={1492-501}
}
Nuclear receptor corepressor (NCoR) mediates transcriptional repression by unliganded nuclear receptors and certain steroid hormone receptors (SHRs) bound to nonphysiological antagonists, but has not been found to regulate SHRs bound to their natural ligands. This report demonstrates that NCoR interacts directly with the androgen receptor (AR) and represses… CONTINUE READING