Inhibition of the butyrylcholinesterase by ethidium bromide.

  title={Inhibition of the butyrylcholinesterase by ethidium bromide.},
  author={Jiř{\'i} Pato{\vc}ka},
  journal={Biomedica biochimica acta},
  volume={46 11},
The effect of ethidium bromide (3,8-diamino-5-ethyl-6-phenyl-phenanthridinium bromide) on the activity of purified horse serum butyrylcholinesterase in vitro has been studied. Ethidium bromide is a middle reversible inhibitor with complex mixed competitive-noncompetitive inhibition kinetics. The inhibitor is bound to the anionic site of the enzyme surface. 

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