Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo

@inproceedings{Pan2013InhibitionOT,
  title={Inhibition of the angiogenesis and growth of Aloin in human colorectal cancer in vitro and in vivo},
  author={Qin Pan and Hongming Pan and Haizhou Lou and Yinghua Xu and Lu Tian},
  booktitle={Cancer Cell International},
  year={2013}
}
Angiogenesis has been an attractive target for drug therapy. Aloin (AL), an natural compound derived from Aloe barbadensis Miller leaves, has been shown to possess anti-cancer potential activities. However, its roles in tumor angiogenesis and the involved molecular mechanism are unknown. To evaluate the antiangiogenic and anticancer activities of AL, endothelial cell scratch, modified Boyden chamber inserts and tube formation assays were done in HUVECs, and MTT and Live-Dead assays were used to… CONTINUE READING
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