Inhibition of the Activity of Recombinant HIV-1 Integrase by Derivatives of Higher Terpenoids


The anti-HIV activity of glycyrrhizic acid, a representative of higher terpenoids, was shown for the first time, using cell cultures, in 1988 [1]. Later, the preparation created on the basis of glycyrrhizic acid was used in practice for treating HIV-infected patients [2]. It was shown that glycyrrhizic acid derivatives and other terpenoids (ursolic and… (More)
DOI: 10.1023/A:1025113525466

4 Figures and Tables


  • Presentations referencing similar topics