Inhibition of telomerase potentiates enzalutamide efficiency of androgen-sensitive human prostate cancer cells.

Abstract

PURPOSE Androgen deprivation therapy (ADT) is one of the main strategies to treat prostate cancer (PCa) at various stages of its development. Androgen receptor (AR) antagonists such as enzalutamide are mainstay treatments for castration-sensitive prostate cancer. Though, a majority of patients initially respond to ADT, most will eventually progress to… (More)

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