Inhibition of synaptically evoked cortical acetylcholine release by adenosine: an in vivo microdialysis study in the rat

@article{Materi2000InhibitionOS,
  title={Inhibition of synaptically evoked cortical acetylcholine release by adenosine: an in vivo microdialysis study in the rat},
  author={Leticia Michelle. Materi and Douglas Rasmusson and Kazue Semba},
  journal={Neuroscience},
  year={2000},
  volume={97},
  pages={219-226}
}
The release of cortical acetylcholine from the intracortical axonal terminals of cholinergic basal forebrain neurons is closely associated with electroencephalographic activity. One factor which may act to reduce cortical acetylcholine release and promote sleep is adenosine. Using in vivo microdialysis, we examined the effect of adenosine and selective adenosine receptor agonists and antagonists on cortical acetylcholine release evoked by electrical stimulation of the pedunculopontine tegmental… CONTINUE READING
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