Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme.

@article{Wang1991InhibitionOS,
  title={Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme.},
  author={Eugenia Wang and William P. Norred and Charles W Bacon and Ronald T. Riley and Alfred H. Merrill},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 22},
  pages={14486-90}
}
Culture materials and grains contaminated with certain isolates of Fusarium moniliforme cause equine leucoencephalomalacia, porcine pulmonary edema syndrome, and liver cancer in rats. The causative agents are thought to be a family of compounds called fumonisins, which bear considerable structural similarity to the long-chain (sphingoid) base backbones of… CONTINUE READING